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Volume 1, Issue 3 , Pages 220-225 , September 2006

A pediatric case of neurofibromatosis type 2 presenting as a plexiform schwannoma of the intraparotid facial nerve: A review of the world literature on the presenting pathology

Jennifer Guillemaud
- Department of Pediatrics, The Stollery Children's Hospital, Edmonton, Canada
Hamdy El-Hakim
- Pediatric Otolaryngology, Division of Pediatric Surgery, The Stollery Children's Hospital, 2C3.59 Walter MacKenzie Health Science Centre, 8440-112 St., Edmonton, Alta. T6G 2B7, Canada
- Corresponding author. Tel.: +1 780 407 8629; fax: +1 780 407 2004.
Nitin Chauhan
- Department of Pediatrics, The Stollery Children's Hospital, Edmonton, Canada
Mark Lee
- Department of Laboratory Medicine and Pathology, The Stollery Children's Hospital, Edmonton, Canada
Michelle Noga
- Department of Radiology, The Stollery Children's Hospital, Edmonton, Canada
Hadi Seikaly
- Division of Otolaryngology, Department of Surgery, The Stollery Children's Hospital, Edmonton, Canada

Received 24 March 2006 ,Revised 31 May 2006 ,Accepted 1 June 2006.

(A) External aspect of mass. (B) Intra-oral aspect of mass. (C) Resected facial nerve and tumor.

(A) External aspect of mass. (B) Intra-oral aspect of mass. (C) Resected facial nerve and tumor.
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(A) An axial gadolinium-enhanced T1 weighted fat-saturated image. *, plexiform schwannoma of the facial nerve; M, masseter muscle; P, Parotid gland; V, posterior facial vein. (B) An axial gadolinium-e

(A) An axial gadolinium-enhanced T1 weighted fat-saturated image. *, plexiform schwannoma of the facial nerve; M, masseter muscle; P, Parotid gland; V, posterior facial vein. (B) An axial gadolinium-enhanced T1 weighted image of the interior auditory canals. The arrows point to bilateral vestibular schwannomas. (C) A sagittal gadolinium-enhanced T1 weighted image of the thoracic spine. *, intramedullary ependymoma, S, syrinx.
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(A) Whole mount of one portion of the patient's tumor demonstrating the nodular architecture. (B) Representative cellular portion of tumor, demonstrating conspicuous nuclear palisading (H & E, 10×). (;

(A) Whole mount of one portion of the patient's tumor demonstrating the nodular architecture. (B) Representative cellular portion of tumor, demonstrating conspicuous nuclear palisading (H & E, 10×). (C) Immunohistochemical staining for S-100 protein (20×). Note the diffuse and strong positivity.
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