International Journal of Pediatric Otorhinolaryngology Extra
Volume 1, Issue 3 , Pages 220-225 , September 2006

A pediatric case of neurofibromatosis type 2 presenting as a plexiform schwannoma of the intraparotid facial nerve: A review of the world literature on the presenting pathology

  • Jennifer Guillemaud

      Affiliations

    • Department of Pediatrics, The Stollery Children's Hospital, Edmonton, Canada
    • ,
  • Hamdy El-Hakim

      Affiliations

    • Pediatric Otolaryngology, Division of Pediatric Surgery, The Stollery Children's Hospital, 2C3.59 Walter MacKenzie Health Science Centre, 8440-112 St., Edmonton, Alta. T6G 2B7, Canada
    • Corresponding Author InformationCorresponding author. Tel.: +1 780 407 8629; fax: +1 780 407 2004.
    • ,
  • Nitin Chauhan

      Affiliations

    • Department of Pediatrics, The Stollery Children's Hospital, Edmonton, Canada
    • ,
  • Mark Lee

      Affiliations

    • Department of Laboratory Medicine and Pathology, The Stollery Children's Hospital, Edmonton, Canada
    • ,
  • Michelle Noga

      Affiliations

    • Department of Radiology, The Stollery Children's Hospital, Edmonton, Canada
    • ,
  • Hadi Seikaly

      Affiliations

    • Division of Otolaryngology, Department of Surgery, The Stollery Children's Hospital, Edmonton, Canada

Received 24 March 2006 ,Revised 31 May 2006 ,Accepted 1 June 2006.

References 

  1. Chiang CW, Chang YL, Lou PJ. Multicentricity of intraparotid facial nerve schwannomas. Ann. Otol. Rhinol. Laryngol. 2001;110:871–874
  2. Caughey RJ, May M, Schaitkin BM. Intraparotid facial nerve schwannoma: Diagnosis and management. Otolaryngol. Head Neck Surg. 2004;130:586–592
  3. Barnes L, Peel RL, Verbin RS. Tumors of the nervous system. In:  Barnes L editors. Surgical Pathology of the Head and Neck. 1st ed.. New York: Marcel Dekker Inc.; 1985;p. 553–663
  4. Chung SY, Kim DI, Lee BH, Yoon PH, Jeon P, Chung TS. Facial nerve schwannomas: CT and MR findings. Yonsei Med. J. 1998;39:148–153
  5. Chen JM, Moll C, Wichmann W, Kurrer MO, Fisch U. Magnetic resonance imaging and intraoperative frozen sections in intratemporal facial schwannomas. Am. J. Otol. 1995;16:68–74
  6. Hehar SS, Dugar J, Sharp J. The changing faces of a parotid mass. J. Laryngol. Otol. 1999;113:938–941
  7. Avery AP, Sprinkle PM. Benign intraparotid schwannomas. Laryngoscope. 1972;82:199–203
  8. Fletcher CD, Davies SE. Benign plexiform (multinodular) schwannoma: A rare tumour unassociated with neurofibromatosis. Histopathology. 1986;10:971–980
  9. Megahed M. Plexiform schwannoma. Am. J. Dermatopathol. 1994;16:288–293
  10. Reith JD, Goldblum JR. Multiple cutaneous plexiform schwannomas. Report of a case and review of the literature with particular reference to the association with types 1 and 2 neurofibromatosis and schwannomatosis. Arch. Pathol. Lab. Med. 1996;120:399–401
  11. Woodruff JM, Scheithauer BW, Kurtkaya-Yapicier O, Raffel C, Amr SS, LaQuaglia MP, et al. Congenital and childhood plexiform (multinodular) cellular schwannoma: a troublesome mimic of malignant peripheral nerve sheath tumor. Am. J. Surg. Pathol. 2003;27:1321–1329
  12. Agaram NP, Prakash S, Antonescu CR. Deep-seated plexiform schwannoma: a pathologic study of 16 cases and comparative analysis with the superficial variety. Am. J. Surg. Pathol. 2005;29:1042–1048
  13. Ishida T, Kuroda M, Motoi T, Oka T, Imamura T, Machinami R. Phenotypic diversity of neurofibromatosis 2: association with plexiform schwannoma. Histopathology. 1998;32:264–270
  14. Val-Bernal JF, Figols J, Vazquez-Barquero A. Cutaneous plexiform schwannoma associated with neurofibromatosis type 2. Cancer. 1995;76:1181–1186
  15. Lalwani A. Neurofibromatosis Type 2. In:  Lalwani A editors. Current Diagnosis and Treatment in Otolaryngology—Head and Neck Surgery. 1st ed.. New York: McGraw-Hill Medical; 2004;p. 833–836
  16. Evans DG, Huson SM, Donnai D, Neary W, Blair V, Newton V, et al. A clinical study of type 2 neurofibromatosis. Q. J. Med. 1992;84:603–618
  17. Evans DG, Birch JM, Ramsden RT. Paediatric presentation of type 2 neurofibromatosis. Arch. Dis. Child. 1999;81:496–499
  18. Nunes F, MacCollin M. Neurofibromatosis 2 in the pediatric population. J. Child Neurol. 2003;18:718–724
  19. Lim HS, Jung J, Chung KY. Neurofibromatosis type 2 with multiple plexiform schwannomas. Int. J. Dermatol. 2004;43:336–340
  20. Iwashita T, Enjoji M. Plexiform neurilemmoma: A clinicopathological and immunohistochemical analysis of 23 tumours from 20 patients. Virchows Arch. A Pathol. Anat. Histopathol. 1987;411:305–309

PII: S1871-4048(06)00064-5

doi: 10.1016/j.pedex.2006.06.001

International Journal of Pediatric Otorhinolaryngology Extra
Volume 1, Issue 3 , Pages 220-225 , September 2006

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