International Journal of Pediatric Otorhinolaryngology Extra
Volume 1, Issue 4 , Pages 297-300 , December 2006

Surgery and calcitonin therapy in childhood central giant cell granuloma

  • Nalan Yazici

      Affiliations

    • Department of Pediatric Oncology, Hacettepe University, Institute of Oncology, 06100 Ankara, Turkey
    • Corresponding Author InformationCorresponding author. Tel.: +90 312 3052990; fax: +90 312 3107018.
  • ,
  • Bilgehan Yalçin

      Affiliations

    • Department of Pediatric Oncology, Hacettepe University, Institute of Oncology, 06100 Ankara, Turkey
  • ,
  • Taner Yilmaz

      Affiliations

    • Department of Otolaryngology–Head & Neck Surgery, Hacettepe University, Faculty of Medicine, 06100 Ankara, Turkey
  • ,
  • Canan Akyüz

      Affiliations

    • Department of Pediatric Oncology, Hacettepe University, Institute of Oncology, 06100 Ankara, Turkey
  • ,
  • Kader Karli Oguz

      Affiliations

    • Department of Radiology, Hacettepe University, Faculty of Medicine, 06100 Ankara, Turkey
  • ,
  • Arzu Sungur

      Affiliations

    • Department of Pathology, Hacettepe University, Faculty of Medicine, 06100 Ankara, Turkey
  • ,
  • Münevver Büyükpamukçu

      Affiliations

    • Department of Pediatric Oncology, Hacettepe University, Institute of Oncology, 06100 Ankara, Turkey

Received 29 July 2006 ,Revised 5 September 2006 ,Accepted 8 September 2006.

  • Image Result

    (A) Central giant cell granuloma of a child. (B) The same child after the surgery and calcitonin treatment.

    (A) Central giant cell granuloma of a child. (B) The same child after the surgery and calcitonin treatment.

  • Image Result

    (A) Initial MR imaging shows left maxillary enhancing tumor which infiltrates nasal cavity and pterygopalatine fossa on fat-suppressed T1-weighted (T1W) spinecho (SE) (TR/TE; 560/12ms). (B) A postcont

    (A) Initial MR imaging shows left maxillary enhancing tumor which infiltrates nasal cavity and pterygopalatine fossa on fat-suppressed T1-weighted (T1W) spinecho (SE) (TR/TE; 560/12ms). (B) A postcontast T1W SE imaging obtained at 1 year of diagnosis displays that lesion increased in size profoundly (T1W SE; 675/15ms). (C) The tumor caused massive destruction–infiltration of the maxillary sinus, zygoma, pterygoid plates and lateral nazal wall as shown on contrast-enhanced CT image. (D) Left maxillary residual tumor with a reduction in outpouching portion is seen on CT examination upon termination of the calcitonin treatment. (E) No residual or recurrent mass is observed on postcontrast transverse images (TR/TE; 500/70ms) performed 22 months after termination of hormonal and surgical treatment.

PII: S1871-4048(06)00087-6

doi: 10.1016/j.pedex.2006.09.002

International Journal of Pediatric Otorhinolaryngology Extra
Volume 1, Issue 4 , Pages 297-300 , December 2006