International Journal of Pediatric Otorhinolaryngology Extra
Volume 3, Issue 2 , Pages 61-65 , March 2008

Case study: Langerhans’ cell histiocytosis (LCH)

  • Nico Jonas

      Affiliations

    • Division of Otolaryngology, University of Cape Town Medical School, South Africa
    • Corresponding Author InformationCorresponding author at: Division of Otolaryngology, University of Cape Town Medical School, H53 Old Main Building, Groote Schuur Hospital, Observatory, Cape Town 7925, South Africa. Tel.: +27 21 4066420; fax: +27 21 4488865.
    • ,
  • Wakisa Mulwafu

      Affiliations

    • Division of Otolaryngology, University of Cape Town Medical School, South Africa
    • ,
  • Sally-Anne Khosa

      Affiliations

    • Department of Anatomical Pathology, Red Cross Children's Hospital, South Africa
    • ,
  • Marc Hendricks

      Affiliations

    • Haematology/Oncology Service, Red Cross Children's Hospital, South Africa

Received 30 May 2007 ,Accepted 4 October 2007.

References 

  1. Histiocytosis Syndromes in Children, Writing Group of the Histiocyte Society, Lancet 1 (8526) (1987) 208–209.
  2. Favara BE, Feller AC, Pauli M, et al. Contemporary classification of histiocytic disorders. The WHO Committee On Histiocytic/Reticulum Cell Proliferations, Reclassification Working Group of the Histiocyte Society. Med. Pediatr. Oncol. 1997;29(3):157–166
  3. Fernandez-Latorre F, Menor-Serrano F, Alonso-Charterina S. Langerhans’ cell histiocytosis of the temporal bone in paediatric patients. AJR. 2000;174:217–221
  4. Goldsmith AJ, Myssiorek D, Valderrama E, Patel M. Unifocal Langerhans’ cell histiocytosis (eosinophilic granuloma) of the petrous apex. Arch. Otolaryngol. Head Neck Surg. 1993;119:113–116
  5. Hermans R, De Foer B, Smet MH, Leysen J. Eosinophilic granuloma of the head and neck: CT and MRI features in three cases. Pediatr. Radiol. 1994;24:33–36
  6. McCaffrey TV, McDonald TJ. Histiocytosis X of the ear and temporal bone: review of 22 cases. Laryngoscope. 1979;89:1735–1742
  7. Irving RM, Broadbent V, Jones NS. Langerhans’ cell histiocytosis in childhood: management of head and neck manifestations. Laryngoscope. 1994;104:64–70
  8. McClain KL, Natkunam Y, Swerdlow SH. Atypical cellular disorders. Hematol. Am. Soc. Hematol. Educ. Program. 2004;283–296
  9. McClain K, Weiss RA. Viruses and Langerhans’ cell histiocytosis: is there a link?. Br. J. Cancer. 1994;70(Suppl. 23):S34–S36
  10. Leahy MA, Krejci SM, Friednash M, et al. Human Herpesvirus 6 is present in lesions of Langerhans’ cell histiocytosis. J. Invest. Dermatol. 1993;101:642–645
  11. Kannourakis GK, Abbas A. The role of cytokines in the pathogenesis of Langerhans’ cell histiocytosis. Br. J. Cancer. 1994;70(Suppl. 13):S37–S40
  12. Bernstrand C, Sandstedt B, Ahstrom L, Henter JI. Long-term follow-up of Langerhans cell histiocytosis: 39 years’ experience of a single centre. Acta Paediatr. 2005;94(8):1073–1084
  13. Broadbent V, Egeler RM, Nesbit ME. Langerhans’ cell histiocytosis: clinical and epidemiological aspects. Br. J. Cancer. 1994;70(Suppl. XXIII):S11–S16
  14. Anonsen CK, Donaldson S. Langerhans’ cell histiocytosis of the head and neck. Laryngoscope. 1987;97:537–541
  15. Hadjigeorgi C, Parpounas C, Zarmakoupis P, Lafoyianni S. Eosinophilic granuloma of the temporal bone: radiological approach in the pediatric patient. Pediatr. Radiol. 1990;20:546–549
  16. Cunningham MJ, Curtin HD, Butkiewicz BL. Histiocytosis X of the temporal bone: CT findings. J. Comput. Assist. Tomogr. 1988;12:70–74
  17. The French Langerhans’ Cell Study Group . A multicentre retrospective survey of Langerhans’ cell histiocytosis: 348 cases observed between 1983 and 1993. Arch. Dis. Child. 1996;75:17–24

PII: S1871-4048(07)00081-0

doi: 10.1016/j.pedex.2007.10.004

International Journal of Pediatric Otorhinolaryngology Extra
Volume 3, Issue 2 , Pages 61-65 , March 2008

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