Pediatric synovial sarcoma of the right masseter muscle: A case report

Summary 

Synovial sarcoma is a rare malignant non-rhabdomyosarcomatous soft-tissue sarcoma in children and adolescents. Only 4% of synovial sarcoma cases develop in the head and neck. Herein, we described a 10-year-old girl with synovial sarcoma of her right masseter muscle. The diagnosis of synovial sarcoma was confirmed by the existence of SYT-SSX fusion gene transcripts, and she was treated with neoadjuvant and adjuvant chemotherapy, surgical resection and postoperative radiotherapy, though standard treatment for synovial sarcoma is complete surgical resection. She remains free of disease 12 months after treatment, and her right masseter muscle has been normal cosmetically and functionally.

Keywords: Synovial sarcoma, Neoadjuvant chemotherapy, Treatment, Diagnosis, SYT-SSX fusion gene