International Journal of Pediatric Otorhinolaryngology Extra
Volume 4, Issue 1 , Pages 1-5 , January 2009

Primary granulocytic sarcoma presenting as an external auditory canal mass in a newborn with a draining ear

  • Laura T. Hetzler

      Affiliations

    • Department of Otolaryngology, Head&Neck Surgery, Loyola University Medical Center, Maywood, IL 60153, USA
    • ,
  • Ricarchito Manera

      Affiliations

    • Department of Pediatric Hematology/Oncology, Loyola University Medical Center, Stritch School of Medicine, Maywood, IL 60153, USA
    • ,
  • Shawn Lapetino

      Affiliations

    • Department of Pathology, Loyola University Medical Center, Stritch School of Medicine, Maywood, IL 60153, USA
    • ,
  • Andrew Hotaling

      Affiliations

    • Department of Otolaryngology, Head&Neck Surgery, Loyola University Medical Center, Maywood, IL 60153, USA
    • Corresponding Author InformationCorresponding author at: Department of Otolaryngology 2160 S. 1st Avenue, Building 105, Room 1870, Maywood, IL 60153, USA. Tel.: +1 708 216 1676; fax: +1 708 216 4834.

Received 1 January 2008 ,Revised 4 March 2008 ,Accepted 7 March 2008.

References 

  1. Hoffman, Hematology: Basic Principles and Practice, 4th ed.
  2. Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE. Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer. 1981;48(September (6)):1426–1437
  3. Lee B, Fatterpekar GM, Kim W, Som Peter M. Granulocytic sarcoma of the temporal bone. AJNR. 2002;23:1497–1499
  4. Porto L, Kieslich M, Schwabe D, Zanella FE, Lanfermann H. Granulocytic sarcoma in children. Neuroradiology. 2004;46(5):374–377
  5. Byrd JC, Edenfield WJ, Shields DJ, Dawson NA. Extramedullary myeloid tumors in acute nonlymphocytic leukemia: a clinical review. J. Clin. Oncol. 1995;13:1800–1816
  6. Menasce LP, Banerjee SS, Beckett E, Harris M. Extra-medullary myeloid tumor (granulocytic sarcoma) is often misdiagnosed: a study of 26 cases. Histopathology. 1999;34:391–398
  7. Binder C, Tiemann M, Haase D, Humpe A, Kneba M. Isolated meningeal chloroma (granulocytic sarcoma)—a case report and review of the literature. Ann. Hematol. 2000;79:459–462
  8. Byrd JC, Weiss RB, Arthur DC, Lawrence D, Baer MR, Davey F, et al. Extramedullary leukemia adversely affects hematologic complete remission rate and overall survival in patients with t(8;21)(q22;q22). J. Clin. Oncol. 1997;15:466–475
  9. Gokcan MK, Batikhan H, Calguner M, Tataragasi AI. Unilateral hearing loss as a presenting manifestation of granulocytic sarcoma (chloroma). Otol. Neurotol. 2006;27(1):106–109
  10. Liu YH, Zhuang HG, Liao XB, Luo XL, Cai XL, Luo DL. Diagnosis and differential diagnosis of granulocytic sarcomas. Zhonghua Xue Ye Xue Za Zhi. 2003;24(11):568–571
  11. Ferri E, Minotto1 C, Ianniello F, Cavaleri S, Armato E, Capuzzo P. Maxillo-ethmoidal chloroma in acute myeloid leukaemia: case report. Acta Otorhinolaryngol. Ital. 2005;25(3):195–199
  12. Rakel, Conn's Current Therapy, 57th ed, 2005.
  13. Tsimberidou AM, Kantarjia HM, Estey E, Cortes JE, Verstovsek S, Faderl S. Outcome in patients with nonleukemic granulocytic sarcoma treated with chemotherapy with or without radiotherapy. Leukemia. 2003;17(6):1100–1103
  14. Muller S, Sangster G, Crocker J, Nar P, Burnett D, Brown G. An immunohistochemical and clinicopathological study of granulocytic sarcoma (‘chloroma’). Hematol. Oncol. 1986;4:101–112
  15. Castillo B, Kaufman L. Pediatr. Clin. North Am. 2003;50(1):149–172
  16. Fonseca NL, Paves L, Nakanami DM, Seixas MT, Manso PG. Orbital granulocytic sarcoma: case report. Arq. Bras Oftalmol. 2005;68(4):557–560
  17. Grainger & Allison's Diagnostic Radiology: A Textbook of Medical Imaging, 4th ed., 2001.
  18. Imrie KR, Kovacs MJ, Selby D, Lipton J, Patterson BJ, Pantalony D, et al. Isolated chloraoma: the effect of early antileukemic therapy. Ann. Int. Med. 1995;123:351–353
  19. Sugimoto Y. Acute myeloid leukemia with t(8;21)(q22;q22) manifesting as granulocytic sarcomas in the rhinopharynx and external acoustic meatus at relapse after high-dose cytarabine: case report and review of the literature. Hematol. J. 2004;5(1):84–89

PII: S1871-4048(08)00023-3

doi: 10.1016/j.pedex.2008.03.003

International Journal of Pediatric Otorhinolaryngology Extra
Volume 4, Issue 1 , Pages 1-5 , January 2009

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