International Journal of Pediatric Otorhinolaryngology Extra
Volume 4, Issue 1 , Pages 36-41, January 2009

Lingual cyst with gastric epithelium: A clinicopathological and immunohistochemical analysis

  • Román Carlos-Bregni

      Affiliations

    • Centro Clínico de Cabeza y Cuello, 6 ave. 7-39 zona 10, ed. Las Brisas of. 501, Ciudad de Guatemala, Guatemala 01010
    • Corresponding Author InformationCorresponding author. Tel.: +502 2363 0769/70; fax: +502 2337 0705.
    • ,
  • Elisa C. Vidaurre

      Affiliations

    • Centro Clínico de Cabeza y Cuello, 6 ave. 7-39 zona 10, ed. Las Brisas of. 501, Ciudad de Guatemala, Guatemala 01010
    • ,
  • Pablo A. Vargas

      Affiliations

    • Department of Oral Pathology, Dental School, University of Campinas, Piracicaba-UNICAMP, Avenue Limeira 901, Caixa Postal 52, CEP 13414-903, Piracicaba, SP, Brazil
    • ,
  • Márcio A. Lopes

      Affiliations

    • Department of Oral Pathology, Dental School, University of Campinas, Piracicaba-UNICAMP, Avenue Limeira 901, Caixa Postal 52, CEP 13414-903, Piracicaba, SP, Brazil
    • ,
  • Jorge E. León

      Affiliations

    • Department of Oral Pathology, Dental School, University of Campinas, Piracicaba-UNICAMP, Avenue Limeira 901, Caixa Postal 52, CEP 13414-903, Piracicaba, SP, Brazil
    • ,
  • Oslei P. Almeida

      Affiliations

    • Department of Oral Pathology, Dental School, University of Campinas, Piracicaba-UNICAMP, Avenue Limeira 901, Caixa Postal 52, CEP 13414-903, Piracicaba, SP, Brazil

Received 29 March 2008; accepted 19 May 2008. published online 08 July 2008.

Summary 

Most cystic lesions of the oral cavity are intraosseous and lined by squamous epithelium. Although rare, various developmental cysts occur preferentially in the tongue, lined by dermal, thyroglossal, gastrointestinal or respiratory epithelium. Surgical excision is the treatment of choice for these cysts. We report the clinical, histological and immunohistochemical aspects of one lingual cyst lined by gastric epithelium affecting a 1-year-old boy. Immunohistochemical analysis showed similar profile of normal gastric epithelium, except by negativity for CK20, suggesting well-differentiation states. The pathogenesis lingual cyst lined by gastric epithelium remains uncertain, but it is considered they are derived from entrapment of embryonic epithelial rests.

Keywords: Tongue, Oral development cyst, Lingual cyst, Gastrointestinal epithelium, Immunohistochemistry

 

PII: S1871-4048(08)00042-7

doi:10.1016/j.pedex.2008.05.005

International Journal of Pediatric Otorhinolaryngology Extra
Volume 4, Issue 1 , Pages 36-41, January 2009

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