International Journal of Pediatric Otorhinolaryngology Extra
Volume 4, Issue 1 , Pages 42-44, January 2009

Inflammatory myofibroblastic tumor larynx mimicking laryngeal papillomatosis

  • Sudesh Kumar

      Affiliations

    • Corresponding Author InformationCorresponding author at: SQUH Hospital, Department of Otolaryngology & Head Neck Surgery, Al Khoud P.O. Box No. 123, Muscat, Oman. Tel.: +968 24144518; fax: +968 24143504.
  • ,
  • A.K. Gupta
  • ,
  • Nandita Kakkar

Department of Otolaryngology & Head Neck Surgery, Postgraduate Institute of Medical Education, Research, Chandigarh, India

Received 29 April 2008; received in revised form 27 May 2008; accepted 27 May 2008. published online 10 July 2008.

Summary 

Inflammatory myofibroblastic tumor (IMT) of larynx is an unusual benign proliferate lesion rarely seen in pediatric age group. A 10-year-old male child presented with history of hoarseness of voice for 6-month duration and indirect laryngoscopy showed an ulcerative, warty growth involving the right vocal cord. The patient underwent microlaryngeal surgery under general anaesthesia and growth was excised completely. The histopathology showed spindle cells arranged in fasciculate pattern with myxoid background and focal hyalinization. The immunostaining showed positivity of spindle cells to vimentin and muscle specific actin confirming the diagnosis of IMT. The voice of child improved after 2 months and had regular follow up for 2 years with no recurrence.

Keywords: Inflammatory myofibroblastic tumor, Larynx, Laryngeal pseudotumor

 

PII: S1871-4048(08)00043-9

doi:10.1016/j.pedex.2008.05.006

International Journal of Pediatric Otorhinolaryngology Extra
Volume 4, Issue 1 , Pages 42-44, January 2009