International Journal of Pediatric Otorhinolaryngology Extra
Volume 5, Issue 1 , Pages 18-22, January 2010

Disseminated aspergillosis with thyroid and bone localization: A case report

  • Cheikhrouhou Fatma

      Affiliations

    • Laboratory of Parasitology and Mycology, Habib Bourguiba UH, Sfax, Tunisia
    • ,
  • Makni Fattouma

      Affiliations

    • Laboratory of Parasitology and Mycology, Habib Bourguiba UH, Sfax, Tunisia
    • ,
  • Sellami Hayet

      Affiliations

    • Laboratory of Parasitology and Mycology, Habib Bourguiba UH, Sfax, Tunisia
    • ,
  • Sellami Amira

      Affiliations

    • Laboratory of Parasitology and Mycology, Habib Bourguiba UH, Sfax, Tunisia
    • ,
  • Hadrich Ines

      Affiliations

    • Laboratory of Parasitology and Mycology, Habib Bourguiba UH, Sfax, Tunisia
    • ,
  • Mahfoudh Abdelmajid

      Affiliations

    • Pediadric Ward of Sfax Hedi Chaker UH, Sfax, Tunisia
    • ,
  • Hachicha Mongia

      Affiliations

    • Pediadric Ward of Sfax Hedi Chaker UH, Sfax, Tunisia
    • ,
  • Chtourou Khalil

      Affiliations

    • Nucleic Medicine Ward of Habib Bourguiba UH, Sfax, Tunisia
    • ,
  • Guermazi Fadhel

      Affiliations

    • Nucleic Medicine Ward of Habib Bourguiba UH, Sfax, Tunisia
    • ,
  • Ayadi Ali

      Affiliations

    • Laboratory of Parasitology and Mycology, Habib Bourguiba UH, Sfax, Tunisia
    • Corresponding Author InformationCorresponding author at: Fungal and Parasitic Molecular Biology Laboratory, School of Medicine, Sfax, Tunisia. Tel.: +216 74247130; fax: +216 74247130.

Received 12 September 2008; received in revised form 9 January 2009; accepted 12 January 2009. published online 09 March 2009.

Summary 

We describe an original case of disseminated aspergillosis (pulmonary, thyroid and vertebral) in a 13-year-old girl from Tunisia. The patient had presented a thyroid node and a knee mass. The scintigraphy confirmed the cold thyroid node and an increased bone uptake in the left knee, the 5th left coast, the femur and the hip. The histological and mycological examinations concluded to an aspergillosis with Aspergillus flavus. The outcome was rapidly fatal.

Few reports have been published on thyroid aspergillosis localization. This major mycosis occurs in children with septic family granulomatosis whose forecast remains dark.

Keywords: Aspergillus flavus, Thyroid, Bone, Disseminated aspergillosis

 

PII: S1871-4048(09)00005-7

doi:10.1016/j.pedex.2009.01.005

International Journal of Pediatric Otorhinolaryngology Extra
Volume 5, Issue 1 , Pages 18-22, January 2010

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