International Journal of Pediatric Otorhinolaryngology Extra
Volume 5, Issue 2 , Pages 74-78 , March 2010

Eosinophilic granuloma of the temporal bone with extensive bilateral otic capsule involvements: Incomplete reossification despite theraphy

  • Ulas Savas Yavas

      Affiliations

    • Eskisehir Osmangazi University, Faculty of Medicine, Department of Radiology, Eskisehir 26140, Turkey
    • ,
  • Armagan Incesulu

      Affiliations

    • Eskisehir Osmangazi University, Faculty of Medicine, Department of Ear-Nose-Throat, Eskisehir 26140, Turkey
    • ,
  • Mustafa Acikalin

      Affiliations

    • Eskisehir Osmangazi University, Faculty of Medicine, Department of Pathology, Eskisehir 26140, Turkey
    • ,
  • Cuneyt Calisir

      Affiliations

    • Eskisehir Osmangazi University, Faculty of Medicine, Department of Radiology, Eskisehir 26140, Turkey
    • Corresponding Author InformationCorresponding author at: 501 Saint Paul Street 1406, Baltimore, MD 21202, USA.
    • ,
  • Baki Adapinar

      Affiliations

    • Eskisehir Osmangazi University, Faculty of Medicine, Department of Radiology, Eskisehir 26140, Turkey

Received 13 February 2009 ,Accepted 2 March 2009.

  • Image Result

    (a, b) Axial and coronal bone window computed tomography reveals destructive lesions of bilateral mastoid with bilateral otic capsule involvement.

    (a, b) Axial and coronal bone window computed tomography reveals destructive lesions of bilateral mastoid with bilateral otic capsule involvement.

  • Image Result

    (a) Axial T1-weighted image (TR/TE, 525/14) shows bilaterally inhomogeneous iso-hyperintense neoplastic soft-tissue masses in the mastoid, tympanic cavity, petrous apex and otic capsule. (b) Axial T2-

    (a) Axial T1-weighted image (TR/TE, 525/14) shows bilaterally inhomogeneous iso-hyperintense neoplastic soft-tissue masses in the mastoid, tympanic cavity, petrous apex and otic capsule. (b) Axial T2-weighted image (TR/TE, 3635/120). The lesion is iso-hyperintense. (c) Axial gadolinum enhanced T1-weighted image (TR/TE, 624/14). There is heterogeneous enhancement.

  • Image Result
    (a) Langerhans’ cells showing lobulated or indented nuclei with occasional longitudinal grooves admixed with eosinophils (H&E ×400). (b) Strong immunoreactivity of the Langerhans’ cells for CD1a (×400;

    (a) Langerhans’ cells showing lobulated or indented nuclei with occasional longitudinal grooves admixed with eosinophils (H&E ×400). (b) Strong immunoreactivity of the Langerhans’ cells for CD1a (×400).

  • Image Result
    (a) Axial bone window computed tomography 14 months after medication. The bony lesions of temporal bone reossified. (b) Axial bone window computed tomography reveals that right lateral semicircular ca

    (a) Axial bone window computed tomography 14 months after medication. The bony lesions of temporal bone reossified. (b) Axial bone window computed tomography reveals that right lateral semicircular canal is dehiscence. (c) Oblique bone window computed tomography reveals that right posterior semicircular canal is dehiscence. (d) Axial bone window computed tomography reveals that left posterior semicircular canal is dehiscence.

PII: S1871-4048(09)00021-5

doi: 10.1016/j.pedex.2009.03.003

International Journal of Pediatric Otorhinolaryngology Extra
Volume 5, Issue 2 , Pages 74-78 , March 2010

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