International Journal of Pediatric Otorhinolaryngology Extra
Volume 6, Issue 1 , Pages 42-44 , January 2011

Second osteosarcoma of mandible after rhabdomyosarcoma of the cheek

  • Serhan Küpeli

      Affiliations

    • Department of Pediatric Oncology, Hacettepe University, 06100 Ankara, Turkey
    • Corresponding Author InformationCorresponding author at: Hacettepe University, Institute of Oncology, Department of Pediatric Oncology, Ankara, Turkey. Tel.: +90 3123052990; fax: +90 3123107018.
  • ,
  • Ali Varan

      Affiliations

    • Department of Pediatric Oncology, Hacettepe University, 06100 Ankara, Turkey
  • ,
  • Canan Akyüz

      Affiliations

    • Department of Pediatric Oncology, Hacettepe University, 06100 Ankara, Turkey
  • ,
  • Mustafa Cengiz

      Affiliations

    • Department of Radiation Oncology, Institute of Oncology, Hacettepe University, 06100 Ankara, Turkey
  • ,
  • Kader Karlı Oğuz

      Affiliations

    • Department of Radiology, Faculty of Medicine, Hacettepe University, 06100 Ankara, Turkey
  • ,
  • Gökhan Gedikoğlu

      Affiliations

    • Department of Pathology, Faculty of Medicine, Hacettepe University, 06100 Ankara, Turkey
  • ,
  • Münevver Büyükpamukçu

      Affiliations

    • Department of Pediatric Oncology, Hacettepe University, 06100 Ankara, Turkey

Received 6 January 2010 ,Revised 14 February 2010 ,Accepted 15 February 2010.

  • Image Result

    (A) Axial postcontrast CT study shows a huge homogenous soft tissue mass in the left cheek. (B) At 3 months follow-up imaging following six courses of chemotherapy a residual soft tissue mass of about

    (A) Axial postcontrast CT study shows a huge homogenous soft tissue mass in the left cheek. (B) At 3 months follow-up imaging following six courses of chemotherapy a residual soft tissue mass of about 1.5cm in diameter is seen.

  • Image Result
    (A) Axial postcontrast CT scan at 22 months of diagnosis of rhabdomyosarcoma seen on Fig. 1A shows a new separate mass centered around the mandible with destruction and new bone formation is seen. (B)

    (A) Axial postcontrast CT scan at 22 months of diagnosis of rhabdomyosarcoma seen on Fig. 1A shows a new separate mass centered around the mandible with destruction and new bone formation is seen. (B) On MR imaging, the mass enhances with Gadolinium profoundly and involvement of ipsilateral masticator muscles and parotid gland is seen.

  • Image Result
    Osteoid production and pleomorphic neoplastic cells, H+E (460×).

    Osteoid production and pleomorphic neoplastic cells, H+E (460×).

PII: S1871-4048(10)00013-4

doi: 10.1016/j.pedex.2010.02.001

International Journal of Pediatric Otorhinolaryngology Extra
Volume 6, Issue 1 , Pages 42-44 , January 2011